Drug
use and asthma are both very common realities in the world today. Researchers from the
journal of Pediatric Allergy and Immunology seem to believe that there is correlation
between these two aspects of life. Kallen, Finnstrom, Nygren and Olausson
conducted a study evaluating the effects that drug use during pregnancy and how
it impacted the child's health. Specifically, did drug use during pregnancy
increase the chances of or cause a child to develop asthma. The researchers,
located in Sweden, gathered children born between 1999-2007. They then looked
at the use of prescription drugs for asthma among these children between July
2005-July 2009. The use of drugs was only evaluated in the 2nd and 3rd
trimesters of pregnancy. Kallen et al. also evaluated the chances of maternal
asthma but eliminating cases of children who had mothers who gave birth during
1999-2007 who also received prescription drugs for asthma during July 2005-July
2011. The authors studied the
subjects in terms of maternal drug use of various different drugs that included
odds ratios for birth year, the mothers age BMI (body mass index), smoking and
uniformity. The study showed that among the 11,000+ mothers who showed use of
anti-asthmatic drugs during pregnancy, roughly 2,500 were showed to not have
asthma. This left the overall rate for asthma in their children after the use
of anti-asthmatics was at 2.59%. Data also presented the idea that there was a defined
increase in asthma risk when mothers used drugs during the 2nd and 3rd
trimesters (not including multivitamins, folic acid, iron or minerals). This
data was collected for children with elimination of data of those children
whose mothers had prescription for anti-asthmatics. These findings clearly
imply that use of specific drugs does increase the risk of childhood asthma
among offspring. One limitation of this study is found in the fact that it is
impossible to eliminate all confounds from the study. There are a number of
other factors that occur during pregnancy that could be increasing the chances
of childhood asthma.
Kallen, B., Finnstrom,
O., Nygren, K.G., Olausson, P.O. (2012). Maternal drug use during pregnancy and
asthma risk among children. Pediatric allergy and immunology. 24, 28-32.
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